Tag: B-cell maturation antigen

Jan62025 by adminNo Comments

CAR-T Warning for Secondary Malignancies: Warranted or Not?

Oncology/Hematology > Leukemia — FDA boxed warning led to multiple studies on the issue in 2024 by Mike Bassett, Staff Writer, MedPage Today January 5, 2025 Early in 2024, we reported on the FDA's call for new boxed warnings on the labeling of all approved chimeric antigen receptor (CAR) T-cell therapies for the potential risk for secondary T-cell malignancies. In this report, we follow up on what has happened since. In January 2024, the FDA mandated new boxed warnings on approved B-cell maturation antigen (BCMA)- or CD19-di...

Dec102024 by adminNo Comments

IVIG Prophylaxis in Myeloma Cuts Infections, Ups Survival

Health and Mediacal

SAN DIEGO-- Patients with numerous myeloma who get intravenous immunoglobulin (IVIG) prophylaxis throughout treatment with teclistamab have less infections and much better total survival compared to those who do not get IVIG prophylaxis, according to brand-new findings provided here at the American Society of Hematology (ASH) 2024 Annual Meeting.Amongst 225 successive clients who got a minimum of one treatment for fallen back and/or refractory numerous myeloma, those who got IVIG prophylaxis experienced a considerably longer period of infection-free survival and a nearly threefold longer mean total survival compared to clients who did not get IVIG prophylaxis.IVIG supplements has actually been revealed to avoid serious infections in clients with numerous myeloma, however proof on the very ...