Wednesday, January 15

Tag: Broad Institute

Schizophrenia and aging might share a typical biological basis

Schizophrenia and aging might share a typical biological basis

Science and Nature
Scientists from the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have actually revealed a noticeably comparable suite of modifications in gene activity in brain tissue from individuals with schizophrenia and from older grownups. These modifications recommend a typical biological basis for the cognitive problems frequently seen in individuals with schizophrenia and in the senior. In a research study released in Naturethe group explains how they examined gene expression in more than a million private cells from postmortem brain tissue from 191 individuals. They discovered that in people with schizophrenia and in older grownups without schizophrenia, 2 brain cell types called astrocytes and nerve cells lowered their expression of genes that support the junct...
Vertex will pay 10s of millions to accredit a questionable CRISPR patent

Vertex will pay 10s of millions to accredit a questionable CRISPR patent

Technology
Vertex Pharmaceuticals has actually consented to purchase rights to utilize a dominant CRISPR patent owned by the Broad Institute of Harvard and MIT, preventing a possible suit over its brand-new gene-editing treatment for sickle-cell illness. The contract permits Vertex to begin offering its treatment, authorized last Friday, without worry of patent violation claims. The one-time treatment will be amongst the most costly ever offered, with a cost of $2.2 million. The patent on CRISPR has actually been the fulcrum off a decade-long legal battle after the Broad Institute, a proving ground in Cambridge, Massachusetts, took rights to the most crucial usages of the gene-editing tool in 2014. Broad's patent claims have actually been opposed by the University of California, Berkeley, which st...