New structure offers insight into mRNA export and cancers, and how infections pirate the procedure to contaminate their host
Cryo-EM structures of CBC and CBC-mALYREF2. Credit: eLife (2024 ). DOI: 10.7554/ eLife.91432.3
The main dogma of biology specifies the circulation of hereditary details: It explains how proteins are made from mRNA design templates, which remain in turn made from DNA. Exporting the mRNA from inside the nucleus to the website of protein translation in the cytoplasm is a crucial action for life for eukaryotes like us.
Yi Ren's newest paper, released in eLifeexplains the structure of a protein complex associated with mRNA export that clarifies the underlying molecular system of mRNA export and the function it plays throughout infection by herpes infections. Ren is an assistant teacher in...