fibrosis – TOP DAILY NEWS

Jan52025 by adminNo Comments

ESG Plus Lifestyle Intervention Shows Promise for MASH

TOPLINE:Endoscopic sleeve gastroplasty (ESG) integrated with way of life modifications causes considerable weight-loss and enhances liver health in clients with metabolic dysfunction-- associated steatohepatitis (MASH) and weight problems over 72 weeks.APPROACH:A potential randomized trial was carried out in 4 centers in Spain from April 2018 to December 2020 to evaluate the efficiency and security of ESG as a treatment for MASH in grownups with weight problems (body mass index [BMI]≥ 30).Individuals had phase 0-3 fibrosis, a histological nonalcoholic fatty liver illness (NAFLD) activity rating ≥ 3, and a rating ≥ 1 for both lobular swelling and hepatocyte ballooning.Clients were arbitrarily designated to go through ESG, performed utilizing an endoscopic stitch system, or a sham endoscopy...

‘A Watershed Moment’: GLP-1 Drug Succeeds in Late-Stage MASH Trial

Health and Mediacal

Meeting Coverage > > AASLD-- First favorable stage III research study for a GLP-1 agonist in persistent liver illness by Mike Bassett, Staff Writer, MedPage Today November 20, 2024 Semaglutide (Wegovy) enhanced liver fibrosis in clients with metabolic dysfunction-associated steatohepatitis (MASH) and resulted in higher rates of MASH resolution, an interim analysis of a stage III trial revealed. In part 1 of the so-called ESSENCE trial, treatment with the GLP-1 receptor agonist led to greater week-72 rates of steatohepatitis resolution without getting worse of liver fibrosis (63% vs 34% with placebo) and enhancement in liver fibrosis without in...

SZA Said She Got Her Breast Implants Removed Because ‘They Ended Up Hurting Me’

Health and Mediacal

In the most current episode of the SHE MD podcast, SZA openly discussed why she had her breast augmentation got rid of. The 34-year-old "Snooze" vocalist shared that her mom was detected with breast cancer years back, which her auntie had a mastectomy. Her physician informed her this household history considerably increased her danger of establishing the illness, which affected her choice to reverse the treatment.SZA likewise stated that, when she initially got the implants, she discovered that she had "a lot" fibrosis, a thickening of connective tissue that can establish in the breasts, which her physician eliminated throughout the surgical treatment. She stated she ultimately had the implants eliminated due to the fact that she "didn't feel excellent, and it hurt," describing, "I got met...