News Feature Released: 06 March 2024 Ken Garber1 19659004 Nature Biotechnology 19459009 (2024 )Cite this post 2797 Accesses 58 Altmetric 19659007 Metrics information Business are intending to find little particles that eliminate undruggable proteins. It will not be simple. This is a sneak peek of membership material, gain access to by means of your organization Gain access to alternatives 19459012 Gain access to Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access membership 24,99 EUR/ 30 days cancel at any time Sign up for this journal 19659014 Get 12 print concerns and online gain access to 209,00 EUR annually just 17,42 EUR per concern Lease or purchase this post 19659018 Rates differ by post type from$1.95 to$39.95 Rates might go through regional taxes which are computed throughout checkout Extra gain access to choices: 19659022 Visit 19659023 Find out about institutional memberships 19659024 Read our FAQs 19659025 Contact client assistance Fig. 1: Molecular glue degraders. SEED Therapeutics 19459010 Referrals 19659028 Ting, P. Y. et al. Blood 142 (Suppl. 1), 2( 2023). 19659029 Post Google Scholar Schreiber, S. L. Cell 19459009 70, 365– 368 (1992 ). Post CAS PubMed Google Scholar 19659032 Liu, J. et al. Cell 19459009 66, 807– 815(1991). 19659033 Short Article CAS PubMed Google Scholar Tan, X. et al. 19459021 Nature 446, 640– 645(2007). Post ADS CAS PubMed Google Scholar 19659036 Rui, H., Ashton, K. S., Min, J., Wang, C. & & Potts, P. R. 19459021 RSC Chem. Biol. 4, 192– 215 (2023 ). Post CAS PubMed Central Google Scholar 19659038 Ito, T. et al. Science 327, 1345– 1350(2010). 19659039 Short Article ADS CAS PubMed Google Scholar Krönke, J. et al. 19459021 Science 343, 301– 305(2014 ). 19659041 Post ADS PubMed Google Scholar Lu, G. et al. 19459021 Science 343, 305– 309(2014). 19659043 Post ADS CAS PubMed Google Scholar Gandhi, A. K. et al. 19459021 Br. J. Haematol. 164, 811– 821(2014). Post CAS PubMed Google Scholar Neomorph. Guggenheim 2022 Targeted Protein Degradation Day, https://kvgo.com/guggenheim/neomorph-march-2022 (2022 ). Han, T. et al. 19459021 Science 19459009 356, eaal3755(2017). Post PubMed Google Scholar 19659049 Słabicki, M. et al. Nature 585, 293– 297(2020). Short Article PubMed Central Google Scholar 19659051 Garber, K. 19459021 Nat. Biotechnol. 40, 12– 16 (2022 ). Post CAS PubMed Google Scholar 19659053 Mayor-Ruiz, C. et al. Nat. Chem. Biol. 16, 1199– 1207 (2020). Post » 19659055 … Learn more